Top 200 Pharmaceutical Products by Retail Sales in 2018
No. | Brand name | Ingredient name | Volume( Billion US$) | Application |
1 | Humira | Adalimumab | 20.484 | Immunology |
2 | Revlimid | Lenalidomide | 9.685 | Oncology |
3 | Enbrel | Etanercept | 7.935 | Immunology |
4 | Opdivo | Nivolumab | 7.567 | Oncology |
5 | Keytruda | Pembrolizumab | 7.171 | Oncology |
6 | Remicade | Infliximab | 7.085 | Autoimmune Disorders |
7 | Herceptin | Trastuzumab | 7.052 | Oncology |
8 | Avastin | Bevacizumab | 6.917 | Oncology |
9 | Mabthera | Rituximab | 6.858 | Oncology |
10 | Eylea | Aflibercept | 6.654 | Ophthalmology |
11 | Xarelto | Rivaroxaban | 6.58 | Cardiovascular Diseases |
12 | Eliquis | Apixaban | 6.438 | Cardiovascular Diseases |
13 | Imbruvica | Ibrutinib | 6.205 | Oncology |
14 | Prevnar 13 | PCV7 Vaccine | 5.803 | Vaccine |
15 | Basaglar | Insulin Glargine | 5.779 | Diabetes |
16 | Stelara | Ustekinumab | 5.251 | Immunology |
17 | Lyrica | Pregabalin | 5.216 | Neurological Disorders |
18 | Neulasta | Pegfilgrastim | 4.683 | Blood Disorders |
19 | Genvoya | (Elvitegravir,Cobicistat,Emtricitabine,Tenofovir Alafenamide) | 4.624 | Infectious Diseases |
20 | Prolia | Denosumab | 4.467 | Oncology |
21 | Tecfidera | Dimethyl Fumarate | 4.296 | Neurological Disorders |
22 | Victoza | Liraglutide | 4.23 | Diabetes |
23 | Ibrance | Palbociclib | 4.118 | Oncology |
24 | Gilenya | Fingolimod | 3.858 | Neurological Disorders |
25 | Lucentis | Ranibizumab | 3.722 | Ophthalmology |
26 | Januvia | Sitagliptin | 3.686 | Diabetes |
27 | Xtandi | Enzalutamide | 3.649 | Oncology |
28 | Botox | Onabotulinumtoxin A | 3.577 | Renal Disorders |
29 | Soliris | Eculizumab | 3.563 | Blood Disorders |
30 | Triumeq | (Abacavir,Dolutegravir & Lamivudine) | 3.522 | Infectious Diseases |
31 | Zytiga | Abiraterone Acetate | 3.498 | Oncology |
32 | Mavyret | Glecaprevir & Pibrentasvir | 3.438 | Infectious Diseases |
33 | Trulicity | Dulaglutide | 3.393 | Diabetes |
34 | Advair | Salmeterol | 3.33 | Respiratory Disorders |
35 | Simponi Aria | Golimumab | 3.319 | Immunology |
36 | Gardasil 9 | HPV Quadrivalent Vaccine | 3.151 | Vaccine |
37 | Humalog | Insulin Lispro | 3.102 | Diabetes |
38 | Truvada | Emtricitabine & Tenofovir Disoproxil | 2.997 | Infectious Diseases |
39 | Xolair | Omalizumab | 2.97 | Respiratory Disorders |
40 | Invega Sustenna | Paliperidone Palmitate | 2.928 | Neurological Disorders |
41 | Symbicort | Budesonide & Formoterol | 2.926 | Respiratory Disorders |
42 | Fiasp | Insulin Aspart | 2.903 | Diabetes |
43 | Orencia | Abatacept | 2.859 | Immunology |
44 | Cosentyx | Secukinumab | 2.837 | Immunology |
45 | Perjeta | Pertuzumab | 2.801 | Oncology |
46 | Spiriva | Tiotropium | 2.726 | Respiratory Disorders |
47 | Aranesp | Darbepoetin Alfa | 2.418 | Blood Disorders |
48 | Ocrevus | Ocrelizumab | 2.377 | Neurological Disorders |
49 | Copaxone | Glatiramer Acetate | 2.366 | Neurological Disorders |
50 | Avonex & Plegridy | Interferon Beta-1 A | 2.363 | Neurological Disorders |
51 | Jardiance | Empagliflozin | 2.309 | Diabetes |
52 | Velcade | Bortezomib | 2.283 | Oncology |
53 | Entyvio | Vedolizumab | 2.276 | Anti-inflammatory |
54 | Sprycel | Dasatinib | 2.275 | Oncology |
55 | Janumet | Metformin & Sitagliptin | 2.228 | Diabetes |
56 | Lipitor | Atorvastatin | 2.207 | Cardiovascular Diseases |
57 | Actemra | Tocilizumab | 2.182 | Immunology |
58 | Tivicay | Dolutegravir | 2.18 | Infectious Diseases |
59 | Jentadueto | Linagliptin | 2.154 | Diabetes |
60 | Alimta | Pemetrexed | 2.133 | Oncology |
61 | Pomalyst | Pomalidomide | 2.04 | Oncology |
62 | Darzalex | Daratumumab | 2.025 | Oncology |
63 | Votubia | Everolimus | 2.02 | Oncology |
64 | Epogen | Epoetin Alfa | 2.014 | Blood Disorders |
65 | Epclusa | Sofosbuvir & Velpatasvir | 1.966 | Infectious Diseases |
66 | Symtuza | Darunavir & Cobicistat | 1.955 | Infectious Diseases |
67 | Tasigna | Nilotinib | 1.874 | Oncology |
68 | Tysabri | Natalizumab | 1.864 | Neurological Disorders |
69 | Aubagio | Teriflunomide | 1.861 | Neurological Disorders |
70 | Tagrisso | Osimertinib | 1.86 | Oncology |
71 | Cialis | Tadalafil | 1.852 | Sexual Health |
72 | Veramyst | Fluticasone Furoate | 1.847 | Respiratory Disorders |
73 | Dupixent | Dupilumab | 1.812 | Dermatology |
74 | Proguad | MMRV Vaccine | 1.798 | Vaccine |
75 | Prograf | Tacrolimus | 1.785 | Immunology |
76 | Sensipar | Cinacalcet | 1.774 | Hormonal Disorders |
77 | Xeljanz | Tofacitinib | 1.773 | Immunology |
78 | Spinraza | Nusinersen | 1.724 | Spinal Muscular Atrophy |
79 | Cimzia | Certolizumab pegol | 1.718 | Anti-inflammatory |
80 | Nexium | Esomeprazole | 1.702 | Gastrointestinal Disorders |
81 | Levemir | Insulin Detemir | 1.679 | Diabetes |
82 | Pradaxa | Dabigatran Etexilate | 1.679 | Blood Disorders |
83 | Lovenox | Enoxaparin | 1.655 | Blood Disorders |
84 | Latuda | Lurasidone | 1.648 | Neurological Disorders |
85 | Plavix | Clopidogrel | 1.627 | Cardiovascular Diseases |
86 | Otezla | Apremilast | 1.608 | Dermatology |
87 | Odefsey | Emtricitabine,Rilpivirine & Tenofovir Alafenamide | 1.598 | Infectious Diseases |
88 | Boostrix | dTap Vaccine | 1.592 | Vaccine |
89 | Sandostatin | Octreotide | 1.587 | Oncology |
90 | Descovy | Emtricitabine & Tenofovir Alafenamide | 1.581 | Infectious Diseases |
91 | Forteo | Teriparatide | 1.576 | Bone and Joint Diseases |
92 | Gleevec | Imatinib | 1.561 | Oncology |
93 | Farxiga | Dapagliflozin | 1.514 | Diabetes |
94 | Abilify Maintena | Aripiprazole | 1.491 | Neurological Disorders |
95 | Kogenate | Antihemophilc Factor | 1.479 | Rare Diseases |
96 | Haemophilia | Human Coagulation Factor Vlla | 1.436 | Blood Disorders |
97 | Crestor | Rosuvastatin | 1.433 | Cardiovascular Diseases |
98 | Novomix | Biphasic Insulin Aspart | 1.422 | Diabetes |
99 | Synagis | Palivizumab | 1.391 | Respiratory Disorders |
100 | Liletta | Levonorgestrel | 1.342 | Sexual Health |
101 | Humulin | Insulin Isophane | 1.331 | Diabetes |
102 | Yervoy | Ipilimumab | 1.33 | Oncology |
103 | Brilinta | Ticagrelor | 1.321 | Cardiovascular Diseases |
104 | TNKase | Alteplase & Tenecteplase | 1.297 | Cardiovascular Diseases |
105 | Abraxane | Paclitaxel Protein Bound | 1.292 | Oncology |
106 | Myrbetriq | Mirabegron | 1.287 | Renal Disorders |
107 | Pulmicort | Budesonide | 1.286 | Respiratory Disorders |
108 | Galvus | Vildagliptin | 1.284 | Diabetes |
109 | Gadavist | Ezetimibe | 1.271 | Cardiovascular Diseases |
110 | Orkambi | Lumacaftor & Ivacaftor | 1.262 | Respiratory Disorders |
111 | Restasis | Cyclosporine | 1.262 | Immunology |
112 | E Keppra | Levetiracetam | 1.254 | Neurological Disorders |
113 | Benicar | Olmesartan Medoxomil | 1.242 | Cardiovascular Diseases |
114 | Vimpat | Lacosamide | 1.241 | Neurological Disorders |
115 | Harvoni | Ledipasvir & Sofosbuvir | 1.222 | Infectious Diseases |
116 | Opsumit | Macitentan | 1.215 | Cardiovascular Diseases |
117 | Atripla | Efavirenz,Entricitabin & Tenofovir Disoproxil Fumarate | 1.206 | Infectious Diseases |
118 | Tresiba | Insulin Degludec | 1.205 | Diabetes |
119 | Biktarvy | Bictegravir,Emtricitabine & Tenofovir Alafenamide | 1.184 | Infectious Diseases |
120 | Novoseven | Coagulation Factor VII | 1.182 | Blood Disorders |
121 | Promacta | Eltrombopag | 1.174 | Oncology |
122 | Creon | Pancrelipase | 1.166 | Rare Diseases |
123 | Juvederm | Hyaluronic Acid | 1.163 | Dermatology |
124 | Tafinlar | Dabrafenib & Trametinib | 1.155 | Oncology |
125 | Isentress | Raltegravir | 1.14 | Infectious Diseases |
126 | Eligard | Leuprorelin | 1.138 | Oncology |
127 | Celecox | Celecoxib | 1.129 | Anti-Inflammatory |
128 | Amlodin | Amlodipine | 1.111 | Cardiovascular Diseases |
129 | Acthar | Corticotropin | 1.11 | Autoimmune Disorders |
130 | Jadenu | Deferasirox | 1.099 | Oncology |
131 | Bexsero | Meningococcal Vaccine | 1.085 | Vaccine |
132 | Chantix | Varenicline | 1.084 | Neurological Disorders |
133 | Sutent | Sunitinib | 1.049 | Oncology |
134 | Shingrix | Zoster Vaccine Recombinant | 1.043 | Vaccine |
135 | Esbriet | Pirfenidone | 1.041 | Autoimmune Disorders |
136 | Faslodex | Fulvestrant | 1.028 | Oncology |
137 | Entresto | Sacubitril & Valsartan | 1.028 | Cardiovascular Diseases |
138 | Diovan HCT | Hydrochlorothiazide & Valsartan | 1.023 | Cardiovascular Diseases |
139 | Kyprolis | Carfilzomib | 1.012 | Oncology |
140 | Kalydeco | Ivacaftor | 1.008 | Respiratory Disorders |
141 | Exforge | Amlodipine & Valsartan | 1.002 | Cardiovascular Diseases |
142 | Kadcyla | Trastuzumab Emtansine | 0.989 | Oncology |
143 | Ventolin | Albuterol | 0.98 | Respiratory Disorders |
144 | Jakavi | Ruxolitinib | 0.977 | Oncology |
145 | Somatuline | Lanreotide | 0.957 | Oncology |
146 | Lumizyme | Algucosidase Alfa | 0.949 | Rare Diseases |
147 | Letairis | Ambrisentan | 0.943 | Cardiovascular Diseases |
148 | Taltz | Ixekizumab | 0.937 | Autoimmune Disorders |
149 | Viagra | Sildenafil | 0.919 | Sexual Health |
150 | Bridion | Sugammadex | 0.917 | Neurological Disorders |
151 | Ofirmev | Acetaminphen | 0.911 | Anti-Inflammatory |
152 | Pneumovax 23 | Pneumococcal Vaccine | 0.907 | Vaccine |
153 | Nuvaring | Ethinyl Estradiol & Etonogestrel | 0.902 | Sexual Health |
154 | Lupron | Leuprolide | 0.892 | Oncology |
155 | Rexulti | Brexpiprazole | 0.884 | Neurological Disorders |
156 | Vesicare | Solifenacin | 0.884 | Renal Disorders |
157 | Lixiana | Edoxaban | 0.881 | Blood Disorders |
158 | Invokamet | Canagliflozin & Metformin Hcl | 0.881 | Diabetes |
159 | Alprolix | Coagulation Factor IX | 0.877 | Blood Disorders |
160 | Vectibix | Panitumumab | 0.872 | Oncology |
161 | Lamictal | Lamotrigine | 0.865 | Neurological Disorders |
162 | Fabrazyme | Agalsidase Beta | 0.853 | Rare Diseases |
163 | Lynparza | Olaparib | 0.834 | Oncology |
164 | Premarins | Conjugated Estrogens | 0.832 | Sexual Health |
165 | Votrient | Pazopanib | 0.828 | Oncology |
166 | Trintellix | Vortioxetine | 0.826 | Neurological Disorders |
167 | Cyramza | Ramucirumab | 0.821 | Oncology |
168 | Edurant | Rilpivirine | 0.816 | Infectious Diseases |
169 | Linzess | Linaclotide | 0.816 | Gastrointestinal Disorders |
170 | Jynarque | Tolvaptan | 0.810 | Cardiovascular Diseases |
171 | Nexavar | Sorafenib | 0.805 | Oncology |
172 | Cerezyme | Imiglucerase | 0.803 | Rare Diseases |
173 | Flovent | Fluticasone Propionate | 0.791 | Respiratory Diseases |
174 | Tecentriq | Atezolizumab | 0.780 | Oncology |
175 | Synthroid | Levothyroxine | 0.776 | Hormonal Disorders |
176 | Symdeko | Tezacaftor & Ivacaftor | 0.769 | Genetic Disorders |
177 | Avodart | Dutasteride | 0.761 | Renal Disorders |
178 | Augmentin | Amoxicillin & Clavulanate | 0.758 | Anti-Bacterial |
179 | Ranexa | Ranolazine | 0.758 | Cardiovascular Diseases |
180 | Zoladex | Goserelin | 0.752 | Oncology |
181 | Nucala | Mepolizumab | 0.749 | Respiratory Disorders |
182 | Pulmozyme | Dornase Alfa | 0.746 | Rare Diseases |
183 | Nplate | Romiplostim | 0.746 | Immunology |
184 | Baraclude | Entecavir | 0.744 | Infectious Diseases |
185 | Noxafil | Posaconazole | 0.742 | Anti-Fungal |
186 | Risperdal Consta | Risperidone | 0.737 | Neurological Disorders |
187 | Aprovel | Irbesartan & Hydrochlorothiazide | 0.737 | Cardiovascular Diseases |
188 | Adempas | Riociguat | 0.731 | Cardiovascular Diseases |
189 | Rotateq | Rotavirus Vaccine | 0.728 | Vaccine |
190 | YAZ | Drospirenone & Ethinyl Estradiol | 0.722 | Sexual Health |
191 | Tarceva | Erlotinib | 0.714 | Oncology |
192 | Seloken | Metoprolol | 0.712 | Cardiovascular Diseases |
193 | Byetta | Exenatide | 0.710 | Diabetes |
194 | Cymbalta | Duloxetine | 0.708 | Neurological Disorders |
195 | Singulair | Montelukast | 0.708 | Respiratory Disorders |
196 | Glucobay | Acarbose | 0.704 | Diabetes |
197 | Nexplanon | Etonogestrel | 0.703 | Sexual Health |
198 | Fluarix | Influenza Vaccine | 0.696 | Vaccine |
199 | Adalat | Nifedipine | 0.690 | Cardiovascular Diseases |
200 | Nexgard | Afoxolaner | 0.689 | Parasitic Infections |