[English name]: Macleaya Cordata Extract

[Botanical Origin]: Macleaya cordata (Willd.) R. Br.

[Appearance]: Orange-red powder

[Sanguinarine]

[Specification]:40% HPLC

[Molecular Formula]: C₂₀H₁₄NO₄

[Molecular weight]：332.33 

[CAS.NO]: 2447-54-3

[Chelerythrine]

[Specification]:18.5% HPLC

[Molecular Formula]: C₂₁H₁₈NO₄

[Molecular weight]：348.37192

[CAS.NO]: 34316-15-9

[Method of Analysis by HPLC]

Column:Hyper ODS2 C18

Mobile phase: Acetonitrile: H2O =40:60

Column temperature:25℃

Flow rate: 1.0ml/min

Detection wavelength: 270nm

[Information]

Macleaya cordata is a bloodroot which owns thousand year history of medicinal usage in China. 13 kinds of alkaloids and other compounds such as sanguinarine, toddaline, protopine, a-allocryptopine, bocconine, rhizoma coptidis alkali, berberine, samin alkali and protopine are in the root and aerial parts. Macleaya cordata extract contains sanguinaine and chelerythrine, which have fungicidal and insecticidal activity. Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-kappaB activation, IkappaBalpha phosphorylation, and degradation.

[Applications]

a. Anti-microbial, to be used in toothpastes, mouthwash, chewing-gum additives and food additives.

b. Insecticidal and anti fungi, to be used as pesticides for crop protection.

c. Substitute of antibiotics in feed additives.

d. Treatment of skin diseases.

[Minimum Inhibitory Concentrations（MIC）]